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ABCs -Group A Streptococcus

Invasive group A streptococcal (GAS) disease ranges from bacteremia and septic arthritis to necrotizing faciitis (NF) and streptococcal toxic shock syndrome (STSS). In children, invasive GAS infections may result as a complication of varicella. Invasive disease is associated with a 10-13% mortality rate, which is even higher for NF and STSS. The traditional Lancefield M protein classification system, which is based on serotyping, has been replaced by emm typing. This gene typing system is based on sequence analysis of the emm gene which encodes the cell surface M protein. Approximately 200 emm types have been identified by CDC thus far. Surveillance for invasive GAS disease provides information on incidence rates, disease type, and risk factors; monitoring of emm types; and contributes to development of disease control guidelines and to special studies.

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Review the Methods and Case Definitions for the EIP ABCs Project

Invasive Group A Streptococcus in Colorado

• Graph - Annual incidence of invasive group A streptococcal disease by age group in Colorado, 2000

• Table - Rates and Case Fatality Percents of Invasive Group A Streptococcal Disease by Age Group: Denver Metropolitan Area, 2001

• Table - Sterile Sites from which Invasive Group A Streptococcus was Isolated: Denver Metropolitan Area, 2001

• Table - Syndromes Associated with Invasive Group A Streptococcal Disease: Denver Metropolitan Area, 2001

• Table - Rates of Invasive Group A Streptococcal Disease by County: Denver Metropolitan Area, 2001

• Table - Most Common Invasive Group A Streptococcal Disease emm Types: Denver Metropolitan Area, 2001

• View past tables:  2000